Zoë Dusanne will become a major influence in introducing modern art to people of the Pacific Northwest. She was the first Seattle dealer to combine professional high standards and nurturance and promotion of Northwest artists with a broad-based desire to educate the local public about modern art, and to educate the world at large about Seattle painters. In this, the Gallery was unique.
In 1958, the house and gallery were demolished to make way for the Seattle Freeway (Interstate-5). On October 4, 1959, Dusanne reopened her gallery at 532 Broadway N, but the new gallery was never able to recoup the losses of the forced move. Dusanne closed the Zoë Dusanne Gallery in 1964.